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Reference Laboratory Tests
20775
21-Hydroxylase Antibody
The microsomal enzyme 21-hydroxylase is the major autoantigen recognized by adrenal cortex autoantibodies, found in chronic primary adrenal insufficiency (Addison’s disease). Autoantibodies to 21-hydroxylase are found in approximately 70% of patients with isolated Addison’s disease, >90% of patients with Addison’s disease as part of autoimmune poyglandular syndrome, and 1 to 5% of patients with other autoimmune endocrine diseases.
*This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Focus Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Test performed at Quest Diagnostics Nichols Institute.
Methodology
RIA (Radioimmunoassay)
Reference Range
<1 U/mL
Preferred Specimen
1 mL serum
(minimum 0.2 mL)
Transport Temperature
2-8° C
Results Available
3 to 29 days
CPT Code
83519*
51590
5-Fluorocytosine Level, BA
Specimens collected just before or within 15 minutes of the next dose represent the TROUGH levels. Specimens obtained within 15-30 minutes after the end of I.V. infusion or 45-60 minutes after an IM injection or 90 minutes after oral intake represent the PEAK level.
Therapeutic levels:
Peak serum
30-45 mcg/mL
List all other antimicrobials being used to treat the patient.
This test is available for New York patient testing.
Methodology
Bioassay
Reference Range
By report
Preferred Specimen
1 mL serum (minimum 0.5 mL) Red Top serum separator tubes not acceptable.