• Immune Complex Detection by C1q Binding
• Immune Complex Expanded Panel
• Immune Complex Panel

• Bacterial Culture, Aerobic, Special

Polyclonal capture anti-RSV antibodies react with RSV antigens present in the specimen sample. Peroxidase-conjugated monoclonal antibodies specific for RSV nucleocapsid antigen are then used to detect the presence of RSV. Sensitivity and specificity of this test approaches 90-95% and 95-100%, respectively.

This test is approved for New York patient testing.

• Borrelia hermsii Antibody Panel, IFA
• Borrelia hermsii Culture
• Borrelia hermsii IgG Antibody, IFA
• Borrelia hermsii IgM Antibody, IFA

Smears are stained with a sensitive fluorescent monoclonal antibody that will detect the presence of RSV in respiratory specimens. This is the recommended test for detection of RSV due to its high sensitivity (90-95%) and specificity (95-100%). DFA can also detect RSV in specimens taken >5 days post onset, when viral isolation becomes increasingly less sensitive due to neutralizing antibodies in respiratory secretions.

This test is approved for New York patient testing.

Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and pneumonia among infants and children under 1 year of age. The detection of RSV RNA is based upon reverse transcription of specific conserved RSV genomic RNA sequences followed by real-time PCR amplification and detection.

This test is not approved for New York patient testing.

Single titers ≧1:64 usually indicate recent RSV infection. A four-fold or greater increase in titer between acute and convalescent specimens is required for diagnosis of RSV infection in adults and children greater than 6 months of age. In contrast, only about 50% of infected children less than 6 months of age exhibit a four-fold or greater increase in titer. Viral isolation and RSV antigen detection methods are recommended for patients less than 6 months old.

This test is approved for New York patient testing.

This unit code has been inactivated.

Please see unit code 40830.

This unit code has been inactivated.

Please see the following unit codes
81150, 81005, 81160 and/or 81165

This assay detects respiratory virus nucleic acid including, RSV, Influenza virus A/B, Parainfluenza virus 1,2, and 3, and Adenovirus, using real-time amplification and detection of specific viral genomic RNA or DNA sequences.

This test is not approved for New York patient testing.

See individual assay for description.

Panel Includes:

• Human Metapneumovirus RNA, Qualitative Real-Time PCR
• Influenza Type A and B RNA, Qualitative Real-Time RT-PCR
• Parainfluenza Virus (Types 1, 2, & 3) RNA, Qualitative Real-Time PCR
• Respiratory Syncytial Virus RNA, Qualitative Real-Time PCR

This assay detects respiratory virus nucleic acid including RSV (respiratory syncytial virus), influenza types A and B, parainfluenza virus (types 1, 2, and 3), adenovirus and hMPV (human metapneumovirus) using real-time amplification and detection of specific viral genomic RNA or DNA sequences.

See individual assay for description.

Panel Includes:

• Adenovirus DNA, Qualitative Real-Time PCR
• Human Metapneumovirus RNA, Qualitative Real-Time PCR
• Influeanza Type A and B RNA, Qualitative Real-Time RT-PCR
• Parainfluenza Virus (Types 1,2 and 3) RNA, Qualitative Real-Time PCR
• Rhinovirus RNA, RT-PCR
• RSV (Respiratory Syncytial Virus) RNA, Qualitative Real-Time PCR

This test is not approved for New York patient testing.

See individual assay for description.

Panel includes:

• Adenovirus DNA, Qualitative Real-Time PCR
• Influenza A H1N1 (2009) Real-Time RT-PCR
• Parainfluenza Virus (Types 1,2, and 3) RNA, Qualitative Real-Time PCR
• RSV (Respiratory Syncytial Virus) RNA, Qualitative Real-Time PCR

This test is not approved for New York patient testing.

The use of centrifugation-enhanced shell vial culture methods combined with sensitive monoclonal antibody staining techniques reduces to less than 72 hours the respiratory virus isolation time that can ordinarily take as much as 14 days by conventional tube culture methods. This test allows for the isolation and identification of Influenza A and B, Parainfluenza virus types 1, 2, and 3, Respiratory Syncytial virus and Adenovirus. Although highly sensitive and much more rapid, this test may be somewhat less sensitive than conventional culture when specimens contain a very low number of viral particles.

This test is approved for New York patient testing.

Reticulin IgA antibody is found in untreated gluten-sensitive enteropathy (60-100%) and dermatitis herpetiformis with celiac mucosal atrophy (90%). The specificity of IgA reticulin antibody is higher for celiac disease than IgG reticulin antibody. If the Reticulin IgA screen is positive, the antibody titer will be performed at and additional charge.

This test is approved for New York patient testing.

 Serologic Tests for Celiac Disease

Reticulin IgG antibody is found in untreated gluten-sensitive enteropathic children and adults dermatitis herpetiformis and small bowel inflammation. The antibody titer may fall after removal of wheat gluten from the diet. The IgG antibody is less specific than the IgA reticulin antibody. If the Reticulin IgG screen is positive, the antibody titer will be performed at an additional charge.

This test is approved for New York patient testing.

 Serologic Tests for Celiac Disease

This unit code has been inactivated.

Please see unit code 21853.

Markedly increased serum titers of rheumatoid factor (RF), >1:80, are consistent with rheumatoid arthritis (RA). Low titers (1:20-1:80) must be interpreted carefully and only used in the diagnosis of RA when signs and symptoms of RA are highly suggestive. Low titers of RF may be seen in chronic infectious disease, acute viral disease, liver disease, sarcoidosis and lymphoproliferative diseases.

This test is approved for New York patient testing.

Rheumatoid factor may be present in synovial fluid in patients with rheumatoid arthritis.

This test is available for New York patient testing.

Elevated levels of rheumatoid factor are found in serum from approximately 75% of patients with clinically diagnosed rheumatoid arthritis.

This test is approved for New York patient testing.

Rhinoviruses are a major cause of respiratory infection, including the common cold. Infection with rhinovirus commonly exacerbates pre-existing airways disease in patients with asthma, COPD, or cystic fibrosis. The detection of rhinovirus RNA is based upon reverse transcription of specific conserved rhinovirus genomic RNA sequences followed by real-time PCR amplification.

This test is not approved for New York patient testing.

This unit code has been inactivated.

Please see unit code 21010.

Ribosomal P antibodies are purported to be associated with the neuropsychiatric manifestations of SLE. Lupus hepatitis is also associated with the presence of ribosomal P antibody.

This test is not approved for New York patient testing.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This panel includes IgG and IgM specific titers against spotted fever group (Rickettsia rickettsii) and typhus fever group (Rickettsia typhi).The spotted fever group includes R. rickettsii (Rocky Mountain Spotted Fever) and R. akari (Rickettsial Pox), both seen in the continental United States. The typhus fever group includes Rickettsia typhi (endemic or murine typhus) and R. prowazeki (epidemic typhus). If Rickettsia antibodies are detected, titers will be performed at an additional charge.

This test is approved for New York patient testing.

See individual assay for description.

Panel Includes:

• Q Fever (Coxiella burnetii) Antibodies (IgG, IgM) with Reflex to Titers
• Rickettsia Antibody Panel with Reflex to Titers

Rickettsia conorii infection, also known as Boutonneuse fever or Mediterranean spotted fever, is found in India, Africa, and the Mediterranean area. Due to the high degree of DNA homology (90%) between R. conorii and R. rickettsii, antibodies from most patients with R. conorii infection are also detected in assays for R. rickettsii antibodies. IgM reactivity in the absence of IgG reactivity may represent a false positive reaction. Recent infection should be confirmed by demonstrating either IgG seroconversion or a four-fold or greater increase in IgG titer when acute and convalescent sera are tested in parallel.

This test is not approved for New York patient testing.

This panel includes IgG and IgM specific titers against Rickettsia rickettsii, the cause of Rocky Mountain Spotted Fever (RMSF). If Rocky Mountain Spotted Fever (RMSF) antibodies are detected, titers will be performed at an additional charge.

This test is approved for New York patient testing.

This unit code has been inactivated.

Please see unit code 40840.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This unit code has been inactivated.

Please see unit code 40840.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

According to the CDC, Rocky Mountain spotted fever is the most severe and most frequently reported rickettsial illness in the United States. Infection is transmitted by ixodid (hard) ticks carried by dogs and other mammal species. Initial signs and symptoms of the disease include sudden onset of fever, headache, and muscle pain, followed by development of rash. The disease can be fatal without prompt treatment.

This test is not approved for New York patient testing.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This panel includes IgG and IgM specific titers against group Rickettsia typhi, the cause of typhus fever. If Rickettsia (Typhus Fever) antibodies are detected, titers will be performed at an additional charge

This test is approved for New York patient testing.

This unit code has been inactivated.

Please see unit code 40855.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This unit code has been inactivated.

Please see unit code 40855.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This unit code has been inactivated.

Please see unit code 51949.

This unit code has been inactivated.

Please see unit code 41000.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This unit code has been inactivated.

Please see unit code 41000.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

This unit code has been inactivated.

Please see unit code 20221.

RNP antibody is found in connective tissue disease (MCTD) (95%), SLE (35%), progressive systemic sclerosis (PSS), rheumatoid arthritis (RA), Sjogren's Syndrom (SS), and discoid lupus. In MCTD elevated levels of RNP antibodies are present in the absence of other auto antibodies to nuclear antigens.

This test is approved for New York patient testing.

This unit code has been inactivated.

Please see unit code 20231.

RNP antibody is present in numerous rheumatic diseases including mixed connective tissue disease (MCTD) (>95%), SLE (35%), progressive systemic sclerosis (PSS), rheumatoid arthritis (RA), Sjögren's Syndrome (SS), and discoid lupus. Sera from MCTD patients typically display elevated antibody levels to only RNP and not to other nuclear antigens. Sm antibody is present in 30% of SLE patients and is a highly specific marker for SLE.

This test is approved for New York patient testing.

• SS-A and SS-B IgG Antibodies, MAID

• Herpesvirus 6 (HHV-6) DNA, Qualitative Real-Time PCR
• Herpesvirus 6 Antibodies (IgG, IgM)
• Herpesvirus 6 Antibody (IgG)
• Herpesvirus 6 Antibody (IgM)

Rotaviruses are the major cause of severe epidemic viral gastroenteritis in infants and young children worldwide, with seasonal outbreaks occurring from November through April in the United States.

This test is approved for New York patient testing.

• Respiratory Syncytial Virus (RSV) Direct Detection, DFA
• Respiratory Syncytial Virus Antibody, CSF
• Respiratory Syncytial Virus Antibody, Serum
• RSV (Respiratory Syncytial Virus) RNA, Qualitative Real-Time PCR

Patient results equal to or greater than 10 IU/mL indicate either past exposure to rubella virus or vaccine, and probable protection from clinical infection. Antibody levels less than 10 IU/mL may be insufficient to provide protection from rubella virus infection.

This test is available for New York patient testing.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is available for New York patient testing.

See individual assay for description.

Panel Includes:

• Rubella IgG, ELISA
• Rubella IgM, ELISA

See individual assay for description.

Panel Includes:

Rubella IgG Antibody, ELISA (CSF) Rubella IgM, ELISA (CSF)

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

Detection of Rubella-specific IgM indicates active infection or recent exposure.

This test is approved for New York patient testing.

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

This test is not approved for New York patient testing.

• Measles (Rubeola) IgG and IgM Antibody Panel, IFA (CSF)
• Measles (Rubeola) IgG and IgM Antibody Panel, IFA (Serum)
• Measles (Rubeola) IgG Antibody (Immunity Screen), IFA (CSF)
• Measles (Rubeola) IgM Antibody, IFA (CSF)

Rubella disease (also known as German measles) is usually a mild disease, but when contracted during pregnancy the virus can infect the fetus and result in congenital rubella syndrome or spontaneous abortion. Vaccination against rubella virus (as part of the MMR combined vaccine) is routine in the United States, but concerns for rubella virus infection exist, however, where rubella vaccine is not administered routinely. This assay used real-time RT-PCR amplification and detection to detect rubella virus RNA.

This test is not approved for New York patient testing.