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Reference Laboratory Tests
22290
Oligoclonal Bands (IgG), CSF
Multiple, discrete oligoclonal IgG bands are present in the CSF of patients with multiple sclerosis (75%-95%) and other subacute or chronic inflammatory neurologic disorders (25%-35%) such as neurosyphilis, subacute sclerosing panencephalitis, meningitis, encephalitis, Guillain-Barré Syndrome and toxoplasmosis. Neither the number nor the pattern of bands correlates with the severity or activity of MS. The presence of oligoclonal IgG bands is a more sensitive indicator of MS than either myelin basic protein (MBP) or the IgG index. Oligoclonal bands are more specific for MS than MBP but less specific than the IgG index.
Test performed at Quest Diagnostics Nichols Institute.
Methodology
IEF (Isoelectric Focusing)
Reference Range
No bands
Preferred Specimen
1 mL CSF
(minimum 0.5 mL)
AND 1 mL serum
(minimum 0.5 mL)
Collection date and time should be the same for both the CSF and Serum.
Transport Temperature
2-8° C
Results Available
2 to 8 days
CPT Code
83916
51730
Ova and Parasite Examination, LM
Testing includes examination of a concentrated wet preparation and a trichrome permanent-stained smear. It is strongly recommended that 3 specimens, collected once per day for 3 days, be submitted. This test does not detect the presence of Cryptosporidium parvum.
This test is approved for New York patient testing.
Methodology
Microscopic: Concentrate and Trichrome
Reference Range
No ova and parasites seen.
Preferred Specimen
Stool or other specimens preserved in PVA and 10% formalin (minimum 5 gram) OR 10 mL urine OR 1 mL sputum
Transport Temperature
Stool: Room temperature
Others: 2-8° C
Results Available
3 to 4 days
CPT Code
87177; 87209
20290
Oligoclonal IgG Bands, IEF
This unit code has been inactivated.
Please see unit code 22290.
-174
Ova and Parasite (See Parasite Examination (Ova and Parasite), LM)
Specimens collected just before or within 15 minutes of the next dose represent the TROUGH levels. Specimens obtained within 15-30 minutes after the end of I.V. infusion or 45-60 minutes after an IM injection or 90 minutes after oral intake represent the PEAK level.
This test is available for New York patient testing.
