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Reference Laboratory Tests
51910
Kanamycin Level, BA
Specimens collected just before or within 15 minutes of the next dose represent the TROUGH levels. Specimens obtained within 15-30 minutes after the end of I.V. infusion or 45-60 minutes after an IM injection or 90 minutes after oral intake represent the PEAK level.
This test is available for New York patient testing.
This assay detects both bound and free light chains in serum. In healthy individuals, over 99% of all serum light chains are bound to heavy chains of circulating immunoglobulins (IgG, IgA, IgM). Increased concentrations of both light chain types in conjunction with a normal ratio indicates polyclonal B cell stimulation, and characterizes chronic inflammatory diseases such as chronic active hepatitis. In contrast, an upward or downward shift in ratio caused by increased kappa chains or increased lambda chains, respectively, usually indicates a monoclonal gammopathy. In these situations, an immunoglobulin evaluation is recommended to identify and characterize any associated paraprotein.
For Free Kappa and Lambda Light Chains see unit code 20646.
This test is approved for New York patient testing.
Methodology
Nephelometry
Reference Range
By report
Preferred Specimen
1 mL serum (minimum 0.5 mL)
Transport Temperature
2-8° C
Results Available
1 to 5 days
CPT Code
83883 x 2
51685
Ketoconazole Level, BA
Specimens collected just before or within 15 minutes of the next dose represent the TROUGH levels. Specimens obtained within 15-30 minutes after the end of I.V. infusion or 45-60 minutes after an IM injection or 90 minutes after oral intake represent the PEAK level.
Therapeutic levels:
Peak serum
4.0 mcg/mL
List all other antimicrobials being used to treat the patient.
This test is available for New York patient testing.
Please see the following technical sheet for more information: Antimicrobial Testing
Methodology
Bioassay
Reference Range
By report
Preferred Specimen
1 mL serum (minimum 0.5 mL) Red Top serum separator tubes not acceptable.
Transport Temperature
FROZEN
Results Available
3 to 4 days
CPT Code
80299
43150
Kappa Light Chain Quantitative, NEPH (Urine)
Both bound and free light chains in urine are detected by nephelometry; bound light chains are still linked to heavy chains of specific immunoglobulins (IgG, IgA, IgM). Approximately 25% of patients with multiple myeloma secrete free light chains only, and another 25% secrete free light chains plus bound light chains. An immunoglobulin evaluation test is recommended to identify and characterize any associated paraprotein.
This test is approved for New York patient testing.
Both bound and free light chains in urine are detected by nephelometry; bound light chains are still linked to heavy chains of specific immunoglobulins (IgG, IgA, IgM). Approximately 25% of patients with multiple myeloma secrete free light chains only, and another 25% secrete free light chains plus bound light chains. An immunoglobulin evaluation test is recommended to identify and characterize any associated paraprotein.
This test is approved for New York patient testing.